Publications

Peaslee C, Esteva-Font C, Su T, Munoz-Howell A, Duwaerts CC, Liu Z, Rao S, Liu K, Medina M, Sneddon JB, Maher JJ, Mattis AN. Doxycycline Significantly Enhances Induction of Induced Pluripotent Stem Cells to Endoderm by Enhancing Survival Through Protein Kinase B Phosphorylation. Hepatology. 2021 Oct;74(4):2102-2117. doi: 10.1002/hep.31898. PMID: 33982322; PMCID: PMC8544023. Duwaerts CC, Le Guillou D, Her CL,

Phillips NJ, Willenbring H, Mattis AN, Maher JJ. Induced Pluripotent Stem Cell-derived Hepatocytes From Patients With Nonalcoholic Fatty Liver Disease Display a Disease-specific Gene Expression Profile. Gastroenterology. 2021 Jun;160(7):2591-2594.e6. doi: 10.1053/j.gastro.2021.02.050. Epub 2021 Feb 25. PMID: 33640436; PMCID: PMC8169560.

Witt RG, Wang B, Nguyen QH, Eikani C, Mattis AN, MacKenzie TC. Depletion of murine fetal hematopoietic stem cells with c-Kit receptor and CD47 blockade improves neonatal engraftment. Blood Adv. 2018 Dec 26;2(24):3602-3607. doi: 10.1182/bloodadvances.2018022020. No abstract available. PMID: 30567724.

Wen KW, Rabinovitch PS, Wang D, Huang D, Mattis AN, Choi WT. Utility of DNA Flow Cytometric Analysis of Paraffin-Embedded Tissue in the Risk Stratification and Management of "Indefinite for Dysplasia" in Patients with Inflammatory Bowel Disease. J Crohns Colitis. 2018 Nov 13. doi: 10.1093/ecco-jcc/jjy193. [Epub ahead of print]. PMID: 30423034.

Wen KW, Rabinovitch PS, Huang D, Mattis AN, Lauwers GY, Choi WT. Use of DNA flow cytometry in the diagnosis, risk stratification, and management of gastric epithelial dysplasia. Mod Pathol. 2018 Oct;31(10):1578-1587. doi: 10.1038/s41379-018-0062-2. Epub 2018 May 22. PMID: 29789650.

Choi WT, Wen KW, Rabinovitch PS, Huang D, Mattis AN, Gill RM. DNA content analysis of colorectal serrated lesions detects an aneuploid subset of inflammatory bowel disease-associated serrated epithelial change and traditional serrated adenomas. Histopathology. 2018 Sep;73(3):464-472. doi: 10.1111/his.13652. Epub 2018 Jun 28. PMID: 29772067.

Schaub JR, Huppert KA, Kurial SNT, Hsu BY, Cast AE, Donnelly B, Karns RA, Chen F, Rezvani M, Luu HY, Mattis AN, Rougemont AL, Rosenthal P, Huppert SS, Willenbring H. De novo formation of the biliary system by TGFβ-mediated hepatocyte transdifferentiation. Nature. 2018 May;557(7704):247-251. doi: 10.1038/s41586-018-0075-5. Epub 2018 May 2. PMID: 29720662.

Pierce AA, Duwaerts CC, Siao K, Mattis AN, Goodsell A, Baron JL, Maher JJ. CD18 deficiency improves liver injury in the MCD model of steatohepatitis. PLoS One. 2017 Sep 5;12(9):e0183912. doi: 10.1371/journal.pone.0183912. eCollection 2017. PMID: 28873429.

Tsai JH, Rabinovitch PS, Huang D, Small T, Mattis AN, Kakar S, Choi WT. Association of Aneuploidy and Flat Dysplasia With Development of High-Grade Dysplasia or Colorectal Cancer in Patients With Inflammatory Bowel Disease. Gastroenterology. 2017 Dec;153(6):1492-1495.e4. doi: 10.1053/j.gastro.2017.08.031. Epub 2017 Aug 24. PMID: 28843957.

Choi WT, Tsai JH, Rabinovitch PS, Small T, Huang D, Mattis AN, Kakar S. Diagnosis and risk stratification of Barrett's dysplasia by flow cytometric DNA analysis of paraffin-embedded tissue. Gut. 2018 Jul;67(7):1229-1238. doi: 10.1136/gutjnl-2017-313815. Epub 2017 Jun 22. PMID: 28642331.

Marco-Rius I, Gordon JW, Mattis AN, Bok R, Delos Santos R, Sukumar S, Larson PEZ, Vigneron DB, Ohliger MA. Diffusion-weighted imaging of hyperpolarized [13 C]urea in mouse liver. J Magn Reson Imaging. 2018 Jan;47(1):141-151. doi: 10.1002/jmri.25721. Epub 2017 Apr 17. PMID: Choi WT, Tsai JH, Rabinovitch PS, Small T, Huang D, Mattis AN, Kakar S. Diagnosis and risk stratification of Barrett's dysplasia by flow cytometric DNA analysis of paraffin-embedded tissue. Gut. 2018 Jul;67(7):1229-1238. doi: 10.1136/gutjnl-2017-313815. Epub 2017 Jun 22. PMID: 28419644.

Spangler B, Fontaine SD, Shi Y, Sambucetti L, Mattis AN, Hann B, Wells JA, Renslo AR. A Novel Tumor-Activated Prodrug Strategy Targeting Ferrous Iron Is Effective in Multiple Preclinical Cancer Models. J Med Chem. 2016 Dec 22;59(24):11161-11170. doi: 10.1021/acs.jmedchem.6b01470. Epub 2016 Dec 12. PMID: 27936709.

Frascoli M, Jeanty C, Fleck S, Moradi PW, Keating S, Mattis AN, Tang Q, MacKenzie TC. Heightened Immune Activation in Fetuses with Gastroschisis May Be Blocked by Targeting IL-5. J Immunol. 2016 Jun 15; 196(12):4957-66. PMID: 27183609.

Zdravkovic T, Nazor KL, Larocque N, Gormley M, Donne M, Hunkapillar N, Giritharan G, Bernstein HS, Wei G,Hebrok M, Zeng X, Genbacev O, Mattis A, McMaster MT, Krtolica A, Valbuena D, Simón C, Laurent LC, Loring JF, Fisher SJ. Human stem cells from single blastomeres reveal pathways of embryonic or trophoblast fate specification. Development. 2015 Dec 1; 142(23):4010-25. PMID: 26483210.

Mattis AN, Song G, Hitchner K, Kim RY, Lee AY, Sharma AD, Malato Y, McManus MT, Esau CC, Koller E, Koliwad S, Lim LP, Maher JJ, Raffai RL, Willenbring H. A screen in mice uncovers repression of lipoprotein lipase by microRNA-29a as a mechanism for lipid distribution away from the liver. Hepatology. 2014 Aug 18. PMCID: PMC4465779.

Zhu S, Rezvani M, Harbell J, Mattis AN, Wolfe AR, Benet LZ, Willenbring H, Ding S. Mouse liver repopulation with hepatocytes generated from human fibroblasts. Nature. 2014 Apr 3; 508(7494):93-7. PMCID: PMC4161230.

Mattis AN, Willenbring H: A ZFN/piggyBac step closer to autologous liver cell therapy. Hepatology, 55(6): pages 2033-2035, 2012. PMID: 22422378

Levy M, Trivedi A, Zhang J, Miles L, Mattis AN, Kim GE, Lassman C, Anders RA, Misdraji J, Yerian LM, Xu H, Dhall D, Wang HL. Expression of glypican-3 in undifferentiated embryonal sarcoma and mesenchymal hamartoma of the liver. Hum Pathol. 2012 May; 43(5):695-701. PMCID: PMC3568522.

Baker-LePain JC, Stone DH, Mattis AN, Nakamura MC, Fye KH. Clinical diagnosis of segmental arterial mediolysis: differentiation from vasculitis and other mimics. Arthritis Care Res (Hoboken). 2010 Nov; 62(11):1655-60. PMCID: PMC2974779.

Mattis AN, Gumport RI, Gardner JF. Purification and characterization of bacteriophage P22 Xis protein. J Bacteriol. 2008 Sep; 190(17):5781-96. PMCID: PMC2519534.

Dichiara JM, Mattis AN, Gardner JF. IntDOT interactions with core- and arm-type sites of the conjugative transposon CTnDOT. J Bacteriol. 2007 Apr; 189(7):2692-701. PMCID: PMC1855790.

Lynch TW, Read EK, Mattis AN, Gardner JF, Rice PA. Integration host factor: putting a twist on protein-DNA recognition. J Mol Biol. 2003 Jul 11; 330(3):493-502. PMID: 12842466.